There are quite a few Slice-of-life anime that are virtually indistinguishable from the kidcoms that Disney Channel airs in terms of content they could get. Nothing in say, Yuru Camp or Kemono Friends is any more objectionable than what you would find in your average Disney Channel cartoon or kidcom. Hell, didn't Disney Channel air K-On in some countries?
Being acquisitions isn't much of a strike against them either because Bluey and Miraculous Lady Bug are also acquisitions and Disney airs them all the time.
No, I think the real reason Disney Channel isn't interested in anime is due to episode count of most non-toyetic family-friendly anime. The aforementioned Yuru Camp and Kemono Friends only have 36 and 24 episodes respectively, and the latter hasn't had its second season dubbed to my knowledge. And those are the ones with both dubs and multiple seasons, most of the others are lucky to have one or the other.
Disney Channel, hell, most TV channels, kids or not, like to air episodes in batches, or at the least daily, and the low episode count of most recent anime combined with the long wait times between seasons is at odds with how most US TV networks operate. Bocchi the Rock would also be great fit for Disney Channel, but A)It doesn't have a dub and B)It only has 12 episodes with no second season in sight. Why wait for PA Works to get production of a second season rolling when they can pick up a show from another country with a higher episode count and a more consistent production schedule, or rely on their original programming where they have more control of production?
Anime is bigger than it has ever been in the US, but the way the anime industry and anime production works means it's more fit for streaming platforms than it is for the hectic US TV landscape. I don't think it's a coincidence anime regained its popularity around the time streaming took off.