If the rumors are true about more versions of Spidey appearing. Heres the ones I hope to see(I'm channeling Spider-Man TAS and Shattered Dimensions here)
*Black-Suit Spider-Man
-A Peter Parker who bonded to the Symbiote but remained in full control.(Harry Osborn becoming Black Spider was a total rip, that should always be Peter's thing)
*Octo-Spider-Man
-A Peter Parker that defeated Doc Ock and took his mechanical arms.
*Six-Armed Spider-Man/Man-Spider
-A Peter Parker that's mutated to have extra arms.
*Silver Armor Spider-Man
-Just like the Spider-Man TAS version, hes essentially Tony Stark in Peter Parker's skin, arrogant, wealthy, owns his company and his identity is public knowledge, everybody loves him even John Jonah Jameson and Uncle Ben is still alive in his reality. Imagine how funny it would be for him to interact with Tony Stark.(A taste of his own medicine)
*Future Foundation Spider-Man
-A Peter Parker that joined the Future Foundation group instead of SHIELD in an alternate reality.
Yeah, I remember those Spideys. Unfortunately, I wouldn't count on seeing those same Spiders in this series; unless they are planning to do a crossover between old Spider-Man's series. I think we should think about the different looks that Spidey had in the current series to imagine the kind of alternative Spiders we could meet in future episodes:
+ Black Suit Spider-Man: A reality were Peter ended trapped inside the Symbiote Venom, just like Flash as Agent Venom. It could be also be an alternative version of Harry Osborn, where he was the one bitten by the radioactive spider instead of Peter. Then, when Venom was created, he ended trapped inside it just like Flash as Agent Venom.
+ Slinger: From "Planet Doom", a Spider-Noir updated to the 21st century. He could really be more useful in the mainstream reality than a guy from the 30s of the past century.
+ Spider-Raptor: From Hulk's series, I think it could be as useful, if not even more, than Spider-Ham. Not trying to insult the Ham, but a Raptor is way more intimidating.
+ "Spider Supreme": A magic Mumbo-Jumbo caused Spider-Man being merged in spirit with Doctor Strange, turning him into the new "Supreme Sorcerer".
+ "Spider-Kung Fu": From "Journey of the Iron Fist". A world where Scorpion possibly managed to kill Iron Fist to take the throne of K'un-Lun, so Spidey had to train in K'un-Lun's ways to stop Scorpion and do the hero thing.
+ "Man-Spider": From "Savage Spider-Man", a Spider-Man whose mutation went more away than usual, becoming more Spider than Man.
+ "Spider Soldier": From "For your Eye only", a Spider-Man more violent, trained in the war's way.
+ "Carnage": I doubt it, but it could be a way to use this character regularly in new episodes.
There was also several "never before seen" Spider back in the comics' version of "Spider-verse", which they could actually work in the animated series. Check them:
+ Spider-Torch: A Spider-man who also gained the powers of the Human Torch.
+ Spider-Tarzan: Spider-Man who, probably, has the role of Ka-Zar in his reality.
+ Spider-Wolverine: Mesmero ended causing Wolverine and Spider-Man fused together?
+ Spider-Hulk: Mesmero did the same thing, but with Hulk?
+ Spider-Fist: A Spider-Man who apparently has the role of Iron Fist in his reality. According to some writers, his version of the "Iron Fist" is using Chi's Energy to create four extra arms; like the classic "six-armed Spider-Man".
+ Spider-Pool: A Spider-Man who went wacko without Aunt May and took the role of Deadpool?
+ Octo Spider: OK, this is like the one of the 90's series.
And there are also some ideas from my mind, about realities where other people was bitten by the radioactive spider instead of Peter Parker. See:
+ Flash Thompson: Possibly like his comic counterpart as "Captain Spider".
+ Mary Jane Watson: I bet she would be like her future daugther, May "Mayday" Parker.
+ Harry Osborn: Either Harry gets extremely corrupted or he realiza that his father is a monster even before he became the Goblin.
Well, opinions?